
Micro Ingredients Berberine 500 mg Per Serving
Cost per serving
$0.07
240 servings · ~240-day supply
Berberine, a plant alkaloid found in goldenseal and barberry, is taken for cholesterol and blood sugar. Below, the berberine products people use ranked by real cost per dose (to the commonly-studied 1,500 mg dose). A value comparison, not medical advice.
Updated September 2026
Promising but low quality: meta-analyses, mostly of small trials from China, report modest reductions in LDL cholesterol and triglycerides at 500 mg two or three times a day, with a high risk of bias. Berberine interacts with several drugs through liver enzymes and is not safe in pregnancy.
Commonly used: 500 mg two to three times a day, with meals.
How this list is built: these are berberine products ranked by real cost per dose across our whole berberine catalogue — not filtered or re-ordered by cholesterol. We don’t hold per-product evidence for a specific use, so we don’t pretend to rank for one. Products whose own label says they are for something else are left out.
Background on berberine from the NIH Office of Dietary Supplements .
The dose, the studies and what to watch for, in full: Berberine as "Nature's Ozempic": Evidence and Cost Per Dose.

Micro Ingredients Berberine 500 mg Per Serving
Cost per serving
$0.07
240 servings · ~240-day supply

Strmuscle Dihydroberberine Supplement 200mg
Cost per serving
$0.09
180 servings · ~180-day supply

NatureBell Berberine 500mg - 300 Capsules - 97% Pure Berberine…
Cost per serving
$0.09
300 servings · ~300-day supply

Cayenne Pepper Softgels
Cost per serving
$0.10
240 servings · ~240-day supply

MONTE VERA Berberine HCL 1500mg with Ceylon Cinnamon…
Cost per serving
$0.11
90 servings · ~90-day supply

DEAL SUPPLEMENT Berberine 500 mg Per Serving
Cost per serving
$0.11
240 servings · ~240-day supply

Micro Ingredients Berberine 1000mg with MCT Oil
Cost per serving
$0.12
240 servings · ~240-day supply

Berberine + Ceylon Cinnamon 500mg
Cost per serving
$0.14
120 servings · ~120-day supply

DRFOSTER Berberine HCL Supplement 1200mg with Ceylon Cinnamon
Cost per serving
$0.14
120 servings · ~120-day supply
See the full ranking, benchmarks and lab-tested brands on best berberine by cost per dose.
Promising but low quality: meta-analyses, mostly of small trials from China, report modest reductions in LDL cholesterol and triglycerides at 500 mg two or three times a day, with a high risk of bias. Berberine interacts with several drugs through liver enzymes and is not safe in pregnancy. This page ranks the products people take by real cost per dose; it does not claim a supplement treats or cures anything. Not medical advice — talk to a clinician about cholesterol.
As of September 2026, the best value we track is Micro Ingredients Berberine 500 mg Per Serving, 240 Softgels | Berberine HCl Supplement from Berberis aristata | Made with Coconut MCT Oil | Non-GMO, Gluten Free. The full ranking by cost per dose is above; Price ÷ servings ÷ dose — the number retailers rarely divide out.
Commonly 500 mg two to three times a day, with meals. This is a general reference, not a prescription — confirm the right amount for you with a clinician. Not medical advice.