
Piping Rock Niacin Supplement 100mg | 300 Tablets | Vitamin B3…
Cost per serving
$0.03
300 servings · ~300-day supply
High-dose niacin (vitamin B3) has long been used to move cholesterol numbers — raising HDL and lowering triglycerides. Below, the vitamin b3 (niacin) products people use ranked by real cost per dose. A value comparison, not medical advice.
Updated September 2026
Niacin does shift the lipid panel, but large trials (AIM-HIGH, HPS2-THRIVE) found that adding it to a statin did NOT reduce heart events and increased side effects. Flushing, liver and blood-sugar effects are real at these doses. Not a self-prescribed cholesterol fix.
Commonly used: gram-level doses are clinical — under supervision only.
How this list is built: these are vitamin b3 (niacin) products ranked by real cost per dose across our whole vitamin b3 (niacin) catalogue — not filtered or re-ordered by cholesterol. We don’t hold per-product evidence for a specific use, so we don’t pretend to rank for one. Products whose own label says they are for something else are left out.
Background on vitamin b3 (niacin) from the NIH Office of Dietary Supplements .

Piping Rock Niacin Supplement 100mg | 300 Tablets | Vitamin B3…
Cost per serving
$0.03
300 servings · ~300-day supply

Carlyle Niacin 100mg | 300 Vegetarian Tablets | Non-GMO
Cost per serving
$0.03
300 servings · ~300-day supply

BulkSupplements.com Niacin Powder - Vitamin B3 Supplement
Cost per serving
$0.04
500 servings · ~500-day supply

BulkSupplements.com Niacinamide Powder - Vitamin B3 Powder
Cost per serving
$0.04
500 servings · ~500-day supply

Source Naturals Niacin
Cost per serving
$0.04
250 servings · ~250-day supply

Vitamatic Niacin (Vitamin B3) 500mg,240 Tablets - Non-GMO…
Cost per serving
$0.04
240 servings · ~240-day supply

CFILIHTC NMN Supplement 500mg - NMN NAD Supplement…
Cost per serving
$0.04
240 servings · ~240-day supply

Vitamin B3 Nicotinamide 1,000mg Per Serving – 500 Capsules
Cost per serving
$0.04
500 servings · ~500-day supply

21st Century Niacinamide 500 mg Prolonged Release Tablets
Cost per serving
$0.05
110 servings · ~110-day supply
See the full ranking, benchmarks and lab-tested brands on best vitamin b3 (niacin) by cost per dose.
Niacin does shift the lipid panel, but large trials (AIM-HIGH, HPS2-THRIVE) found that adding it to a statin did NOT reduce heart events and increased side effects. Flushing, liver and blood-sugar effects are real at these doses. Not a self-prescribed cholesterol fix. This page ranks the products people take by real cost per dose; it does not claim a supplement treats or cures anything. Not medical advice — talk to a clinician about cholesterol.
As of September 2026, the best value we track is Piping Rock Niacin Supplement 100mg | 300 Tablets | Vitamin B3 for Men and Women | Nicotinic Acid with Flushing | Vegetarian, Non-GMO, Gluten Free. The full ranking by cost per dose is above; Price ÷ servings ÷ dose — the number retailers rarely divide out.
Commonly gram-level doses are clinical — under supervision only. This is a general reference, not a prescription — confirm the right amount for you with a clinician. Not medical advice.