NEW
⚡ Alpha-Lipoic Acid
Cost per serving
$0.20
Avg·−54%
other · 19 active deals
The best-value Alpha-Lipoic Acid right now is about $0.06 per dose — across 19 tracked products the median is $0.208/dose, so shopping on cost-per-dose can cut your cost several-fold. Every Alpha-Lipoic Acid deal here is ranked by cost per dose— what you actually pay per serving, not the sticker price — because forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Right now the best value across our full Alpha-Lipoic Acid catalog is at $0.06 per serving.
Alpha-lipoic acid (ALA) is a caprylic acid-derived antioxidant synthesized in the mitochondria, used as a supplement for managing chronic diseases characterized by oxidative stress. It has been studied most for diabetic neuropathy, where it is described as enhancing nitric oxide-mediated endothelium-dependent vasodilation and improving microcirculation, and it has been explored for slowing the onset of metabolic syndrome. The article notes there is still a need for more studies on its benefits in other conditions such as HIV/AIDS, liver disease, and weight loss, and that ALA has no approved indication as a dietary supplement. — per StatPearls (NCBI Bookshelf); not medical advice.
ALA is available as an oral supplement and as an intravenous injection; studied doses include 300 mg over 3 months and 600 mg to 1800 mg daily for up to 6 months orally, and 600 mg daily intravenously for neuropathic symptoms. The article states that absorption, volume of distribution, metabolism, and excretion are not well-established for ALA.
Alpha-lipoic acid is found naturally in red meat, beets, carrots, potatoes, spinach, and broccoli, and is also synthesized in the mitochondria.
Adults can take up to 2400 mg without reported harmful adverse effects, and a daily dose of 200 mg/day to 2400 mg/day is deemed safe in adults, though there is no reported safe dose in children; the most common adverse effects reported are headache, heartburn, nausea, and vomiting. In animal studies, high intravenous doses caused necrosis including in the liver, and one human case involved status epilepticus. — per StatPearls (NCBI Bookshelf).
Patients should consult a physician before use if they have liver disease, high alcohol consumption, diabetes (ALA is known to lower blood sugar), a thyroid disorder, or thiamine deficiency, and should stop using ALA immediately if an allergic reaction such as skin rash, nausea, or vomiting occurs. Research shows ALA supplementation during pregnancy is safe but more data is needed to establish its role, while there is a lack of reliable data regarding safety during breastfeeding. — per StatPearls (NCBI Bookshelf).
Source:
Every Alpha-Lipoic Acid deal above is ranked by real cost per dose with no paid placement — see our and .
1 of 8 tracked Alpha-Lipoic Acid brands here are flagged as carrying independent third-party testing — a voluntary check of a product's identity, potency and contaminants by an outside lab. It's a quality signal, not a value or efficacy claim. Confirm any brand's current status on the official registries:
Testing status is self-reported by the brand or drawn from public certification and may change — always verify on the official registry before purchase.
Alpha-lipoic acid is made by the body and is not an essential nutrient, so there is no . The source describes studied oral ranges such as 300 mg daily over about 3 months and 600 to 1800 mg daily for up to 6 months, and states a daily dose of roughly 200 mg to 2400 mg is deemed safe without significant adverse effects. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
It has been studied for conditions including diabetic neuropathy, oxidative stress, metabolic syndrome, and liver disease, with the source noting that so far it has the most substantial evidence of a therapeutic effect in diabetic neuropathy and oxidative-stress conditions while other uses need more research. This describes what it is studied for, not a confirmed treatment. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
The source generally describes alpha-lipoic acid as a safe supplement, with reported side effects that may include headache, heartburn, nausea, and vomiting; it adds there is no reported safe dose in children, and animal data linked very high doses to liver-enzyme changes. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
The source advises consulting a doctor before use if you have liver disease, a thyroid disorder, thiamine deficiency, diabetes (because alpha-lipoic acid is known to lower blood sugar), or consume large amounts of alcohol, and it notes no reported safe dose in children. It states there is no established contraindication for use in pregnant women and infants. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
We link primary sources and paraphrase their findings — never copy their text, tables, or images. Cost-per-dose figures are our own first-party catalog data.
Cost per serving
$0.20
Avg·−54%Cost per serving
$0.21
Avg·−49%120 servings · ~120-day supply
Cost per serving
$0.22
Avg·−44%Cost per serving
$0.17
Avg·−70%50 servings · ~50-day supply
Cost per serving
$0.40
Pricey60 servings · ~60-day supply
Cost per serving
$0.68
Pricey60 servings · ~60-day supply
Cost per serving
$0.10
Cost per serving
$0.16
Cheap·−75%120 servings · ~120-day supply
Cost per serving
$0.08
Cheap·−88%300 servings · ~300-day supply
Cost per serving
$0.22
Avg·−41%Cost per serving
$0.28
Pricey90 servings · ~90-day supply
Cost per serving
$0.54
Pricey120 servings · ~120-day supply
Cost per serving
$0.21
Avg·−50%120 servings · ~120-day supply
Cost per serving
$0.08
Cheap·−88%240 servings · ~240-day supply
Cost per serving
$0.17
Avg·−72%60 servings · ~60-day supply
Cost per serving
$0.28
PriceyCost per serving
$0.23
Avg·−38%120 servings · ~120-day supply
Cost per serving
$0.06
Cheap·−90%240 servings · ~240-day supply
Cost per serving
$0.16
Avg·−74%Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$35.96
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$25.29
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$19.76
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$8.51
SuperSmart USA LLC · SuperSmart · ⚡ Alpha-Lipoic Acid
CPS
Price
$24.00
Pure Encapsulations · Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$41.00
BulkSupplements.com · Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$22.97
NOW Foods · Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$19.00
Micro Ingredients · Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$23.99
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$26.95
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$24.95
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$64.99
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$24.97
Horbäach · Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$18.99
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$9.95
Doctor's Best · Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$16.99
NOW Foods · Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$27.50
Vitamatic · Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$15.29
Amazon.com · ⚡ Alpha-Lipoic Acid
CPS
Price
$19.45
Vitamatic Alpha Lipoic Acid (ALA) 600mg Per Serving - 240 Vegetable Capsules… at $0.06 per serving — the lowest cost-per-dose alpha-lipoic acid in our catalog. See the full ranking on the Best Alpha-Lipoic Acid page.
We're tracking 19 active Alpha-Lipoic Acid deals across Amazon US and partner retailers, ranked by community votes and cost-per-dose — not paid placement.
Across 19 tracked Alpha-Lipoic Acid deals the median cost-per-dose is $0.208; the cheapest quartile comes in under $0.160 per serving. Anything below the median is a solid deal for the same molecule.
Deals are submitted by the community and ranked by net votes (hot minus cold) plus cost-per-dose normalised across container sizes. We take no affiliate kickbacks for ordering; sponsored slots, when present, are clearly badged.
Adults can take up to 2400 mg without reported harmful adverse effects, and a daily dose of 200 mg/day to 2400 mg/day is deemed safe in adults, though there is no reported safe dose in children; the most common adverse effects reported are headache, heartburn, nausea, and vomiting. In animal studies, high intravenous doses caused necrosis including in the liver, and one human case involved status epilepticus. — per StatPearls (NCBI Bookshelf).
Alpha-lipoic acid is found naturally in red meat, beets, carrots, potatoes, spinach, and broccoli, and is also synthesized in the mitochondria.
Patients should consult a physician before use if they have liver disease, high alcohol consumption, diabetes (ALA is known to lower blood sugar), a thyroid disorder, or thiamine deficiency, and should stop using ALA immediately if an allergic reaction such as skin rash, nausea, or vomiting occurs. Research shows ALA supplementation during pregnancy is safe but more data is needed to establish its role, while there is a lack of reliable data regarding safety during breastfeeding. — per StatPearls (NCBI Bookshelf).
Dosage, upper-limit, deficiency, food-source and interaction facts are sourced from the NIH Office of Dietary Supplements Alpha-Lipoic Acid fact sheet. General information, not medical advice.
180 servings · ~180-day supply
90 servings · ~90-day supply
240 servings · ~240-day supply
120 servings · ~120-day supply
60 servings · ~60-day supply
120 servings · ~120-day supply
