Cost per serving
vitamin · 61 active deals
Every Vitamin B3 deal here is ranked by cost per dose— what you actually pay per serving, not the sticker price. Forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Right now the best value across our full Vitamin B3 catalog is at $0.03 per serving.
Niacin (vitamin B3) is a water-soluble B vitamin that all tissues convert into the coenzyme nicotinamide adenine dinucleotide (NAD) and, in turn, NADP; according to NIH, more than 400 enzymes require NAD — more than for any other vitamin-derived coenzyme. NAD and NADP are required in most cellular redox reactions: NAD helps transfer the energy in carbohydrates, fats, and proteins to ATP and is needed for maintaining genome integrity, controlling gene expression, and cellular communication, while NADP supports anabolic reactions such as cholesterol and fatty-acid synthesis and antioxidant function. Severe niacin deficiency causes pellagra. Niacin has also been studied for cardiovascular disease: NIH notes that very high doses of nicotinic acid can improve blood lipid profiles (raising HDL and lowering LDL, triglycerides, and lipoprotein(a)), but states that despite dozens of trials experts do not agree on its value, and that systematic reviews concluded it provides little if any protection from atherosclerotic heart disease and no significant effect on cardiovascular events — per the NIH Office of Dietary Supplements; not medical advice.
Per NIH, nicotinic acid and nicotinamide are the two most common forms of niacin in supplements, and both are almost completely absorbed. Nicotinic acid can cause skin flushing, so some products are made as prolonged, sustained, extended, or timed release to minimize this, whereas nicotinamide does not cause flushing because of its slightly different chemical structure. Niacin is also sold as inositol hexanicotinate, often labeled "flush free"; NIH states its absorption varies widely but on average is about 30% lower than from nicotinic acid or nicotinamide.
Niacin is present in a wide variety of foods. Many animal-based foods—including poultry, beef, and fish—provide about 5–10 mg niacin per serving in the highly bioavailable forms of NAD and NADP, while plant-based foods such as nuts, legumes, and grains provide about 2–5 mg per serving, mainly as nicotinic acid; the niacin in some grain products is only about 30% bioavailable. Among the richest listed sources are beef liver (14.9 mg per 3 ounces), chicken breast and turkey breast (about 10 mg per 3 ounces), and salmon and tuna (8.6 mg per 3 ounces), and many U.S. breads, cereals, and infant formulas contain added niacin in its free, highly bioavailable form — per the NIH Office of Dietary Supplements.
Severe niacin deficiency leads to pellagra, characterized by a pigmented rash on sun-exposed skin, a bright red tongue, digestive changes such as vomiting, constipation or diarrhea, and neurological symptoms including depression, apathy, headache, fatigue, and memory loss; as it progresses, anorexia develops and the affected individual eventually dies. Although pellagra is very rare in the United States, groups most likely to have inadequate niacin status include people who are undernourished (due to poverty, anorexia, alcohol use disorder, AIDS, inflammatory bowel disease, or liver cirrhosis), people with inadequate riboflavin, pyridoxine (B6), or iron intakes (which reduce tryptophan-to-niacin conversion), and people with Hartnup disease or carcinoid syndrome — per the NIH Office of Dietary Supplements.
No adverse effects have been reported from the consumption of naturally occurring niacin in foods, but high intakes of nicotinic acid and nicotinamide taken as a supplement or medication can cause adverse effects. Thirty to 50 mg or more of nicotinic acid typically causes flushing—reddening of the skin on the face, arms, and chest with burning, tingling, and itching—which is considered an unpleasant rather than toxic side effect but can be accompanied by more serious signs such as headache, rash, dizziness, and a decrease in blood pressure — per the NIH Office of Dietary Supplements.
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$0.11
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$0.16
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$0.27
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$0.68
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$0.22
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$0.54
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$0.27
Cost per serving
$0.08
Avg·−58%Cost per serving
$0.03
Cheap·−84%Cost per serving
$0.14
Avg·−41%Cost per serving
$0.08
Avg·−59%Cost per serving
$0.12
Avg·−45%Cost per serving
$0.09
Avg·−58%Cost per serving
$0.27
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$0.10
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$0.19
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$0.11
Avg·−46%Cost per serving
$0.23
PriceyCost per serving
$0.08
Avg·−62%Cost per serving
$0.05
Cheap·−75%Cost per serving
$0.23
PriceyCost per serving
$0.21
PriceyCost per serving
$0.10
Avg·−50%Amazon.com · 🫀 CoQ10
CPS
Price
$33.42
Amazon.com · 🧬 NMN
CPS
Price
$12.99
Amazon.com · 🧬 NMN
CPS
Price
$18.99
Amazon.com · 🫀 CoQ10
CPS
Price
$31.99
Amazon.com · 🧬 NMN
CPS
Price
$40.99
Amazon.com · 🧬 NMN
CPS
Price
$44.21
Amazon.com · 🧬 NMN
CPS
Price
$48.71
Amazon.com · 🧬 NMN
CPS
Price
$15.96
HerbsPro · ❤️ Vitamin B3
CPS
Price
$8.40
HerbsPro · ❤️ Vitamin B3
CPS
Price
$3.53
HerbsPro · ❤️ Vitamin B3
CPS
Price
$12.28
HerbsPro · ❤️ Vitamin B3
CPS
Price
$8.29
HerbsPro · ❤️ Vitamin B3
CPS
Price
$12.19
HerbsPro · ❤️ Vitamin B3
CPS
Price
$8.52
HerbsPro · 🌸 Inositol
CPS
Price
$13.43
HerbsPro · ❤️ Vitamin B3
CPS
Price
$24.37
HerbsPro · ❤️ Vitamin B3
CPS
Price
$11.55
HerbsPro · ❤️ Vitamin B3
CPS
Price
$10.33
HerbsPro · ❤️ Vitamin B3
CPS
Price
$23.10
HerbsPro · ❤️ Vitamin B3
CPS
Price
$7.74
HerbsPro · ❤️ Vitamin B3
CPS
Price
$5.08
HerbsPro · ❤️ Vitamin B3
CPS
Price
$23.02
HerbsPro · ❤️ Vitamin B3
CPS
Price
$6.29
HerbsPro · ❤️ Vitamin B3
CPS
Price
$18.09
Dosage, upper-limit, deficiency and interaction facts are sourced from the NIH Office of Dietary Supplements Vitamin B3 fact sheet. General information, not medical advice.
$0.28