Cost per serving
$0.10
Avg·−36%vitamin · 26 active deals
Every Vitamin B5 deal here is ranked by cost per dose— what you actually pay per serving, not the sticker price. Forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Right now the best value across our full Vitamin B5 catalog is at $0.05 per serving.
Pantothenic acid (vitamin B5) is an essential water-soluble B vitamin whose main function, according to the NIH Office of Dietary Supplements, is in the synthesis of coenzyme A (CoA) and acyl carrier protein; CoA is essential for fatty acid synthesis and degradation, the transfer of acetyl and acyl groups, and many other anabolic and catabolic processes, while acyl carrier protein's main role is in fatty acid synthesis. Because of pantothenic acid's role in triglyceride synthesis and lipoprotein metabolism, experts have hypothesized that supplementation might reduce lipid levels in people with hyperlipidemia; the NIH notes that several clinical trials have shown the related form pantethine reduces lipid levels when taken in large amounts, but pantothenic acid itself does not appear to have the same effects. It has also been examined in the context of pantothenate kinase-associated neurodegeneration (PKAN), though the NIH states that whether pantothenate supplementation is beneficial in PKAN is not known. The NIH adds that because some pantothenic acid is present in almost all foods, deficiency is rare except in people with severe malnutrition — per the NIH Office of Dietary Supplements; not medical advice.
The NIH Office of Dietary Supplements states that pantothenic acid is available in dietary supplements containing only pantothenic acid, in combination with other B-complex vitamins, and in some multivitamin/multimineral products. Some supplements contain pantethine (a dimeric form of pantetheine) or, more commonly, calcium pantothenate. The NIH notes that no studies have compared the relative bioavailability of pantothenic acid from these different forms.
Almost all plant- and animal-based foods contain pantothenic acid in varying amounts; some of the richest dietary sources are beef, chicken, organ meats, whole grains, and some vegetables. It is also added to various foods, including some breakfast cereals and beverages such as energy drinks. The food highest in pantothenic acid listed is beef liver (8.3 mg per 3 ounces), followed by fortified breakfast cereals, shiitake mushrooms, and sunflower seeds — per the NIH Office of Dietary Supplements.
Because some pantothenic acid is present in almost all foods, deficiency is rare except in people with severe malnutrition; the only individuals known to have developed it were fed diets containing virtually no pantothenic acid or were taking a pantothenic acid metabolic antagonist. The one group noted as most likely to have inadequate status is people with a pantothenate kinase 2 (PANK2) gene mutation causing the rare inherited disorder PKAN. Deficiency is associated with numbness and burning of the hands and feet, headache, fatigue, irritability, restlessness, disturbed sleep, and gastrointestinal disturbances with anorexia — per the NIH Office of Dietary Supplements.
The Food and Nutrition Board was unable to establish a Tolerable Upper Intake Level (UL) for pantothenic acid because there are no reports of pantothenic acid toxicity in humans at high intakes. Some individuals taking large doses (e.g., 10 g/day) develop mild diarrhea and gastrointestinal distress, but the mechanism for this effect is not known — per the NIH Office of Dietary Supplements.
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$0.10
Avg·−36%Cost per serving
$0.12
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$0.10
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$0.18
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$0.07
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$0.10
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$1.99
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$0.11
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$0.06
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$0.05
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$0.08
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$0.09
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$0.003
Cheap·−79%Cost per serving
$1.94
PriceyCost per serving
$0.11
Avg·−30%Cost per serving
$2.99
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$0.001
Cheap·−95%Cost per serving
$0.08
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$0.005
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$0.001
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$0.001
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<$0.001
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$0.001
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$0.14
PriceyAmazon.com · 🔋 Vitamin B5
CPS
Price
$20.79
Amazon.com · 🔋 Vitamin B5
CPS
Price
$11.99
Amazon.com · 🔋 Vitamin B5
CPS
Price
$11.96
Amazon.com · 🔋 Vitamin B5
CPS
Price
$15.75
Amazon.com · 🔋 Vitamin B5
CPS
Price
$17.40
Amazon.com · 🔋 Vitamin B5
CPS
Price
$9.99
Amazon.com · 💪 Protein Powder
CPS
Price
$23.91
HerbsPro · 🔋 Vitamin B5
CPS
Price
$10.50
HerbsPro · 🔋 Vitamin B5
CPS
Price
$6.48
NOW Foods · Amazon.com · 🔋 Vitamin B5
CPS
Price
$12.29
NOW Foods · Amazon.com · 🔋 Vitamin B5
CPS
Price
$7.99
Vitamatic · Amazon.com · 🔋 Vitamin B5
CPS
Price
$18.53
Bluebonnet · Amazon.com · 🔋 Vitamin B5
CPS
Price
$0.16
BulkSupplements.com · Amazon.com · 🔋 Vitamin B5
CPS
Price
$1.94
Nature's Way · Amazon.com · 🔋 Vitamin B5
CPS
Price
$11.10
BulkSupplements.com · Amazon.com · 🔋 Vitamin B5
CPS
Price
$14.97
Source Naturals · Amazon.com · 🔋 Vitamin B5
CPS
Price
$0.06
Solgar · Amazon.com · 🔋 Vitamin B5
CPS
Price
$8.04
Amazon.com · 🔋 Vitamin B5
CPS
Price
$0.42
Amazon.com · 🔋 Vitamin B5
CPS
Price
$0.08
Jarrow Formulas · Amazon.com · 🔋 Vitamin B5
CPS
Price
$0.13
Amazon.com · 🔋 Vitamin B5
CPS
Price
$0.05
Life Extension · Amazon.com · 🔋 Vitamin B5
CPS
Price
$0.10
Source Naturals · Amazon.com · 🔋 Vitamin B5
CPS
Price
$13.97
Dosage, upper-limit, deficiency and interaction facts are sourced from the NIH Office of Dietary Supplements Vitamin B5 fact sheet. General information, not medical advice.