Cost per serving
$0.04
Cheap·−82%vitamin · 54 active deals
Every Vitamin B6 deal here is ranked by cost per dose— what you actually pay per serving, not the sticker price. Forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Right now the best value across our full Vitamin B6 catalog is at $0.005 per serving.
Recommended daily intake
Long-term high doses can cause nerve symptoms; respect the upper limit. General FDA/NIH adult guidance — not medical advice.
Vitamin B6 is a water-soluble vitamin whose coenzyme forms are involved in more than 100 enzyme reactions, mostly concerned with protein and amino acid metabolism, as well as the metabolism of carbohydrates and lipids. It plays a role in cognitive development through the biosynthesis of neurotransmitters, in maintaining normal blood levels of homocysteine, and it is involved in gluconeogenesis and glycogenolysis, immune function, and hemoglobin formation. It has been studied as a supplement for cardiovascular disease (by lowering homocysteine), cancer, cognitive decline in older adults, premenstrual syndrome, and nausea and vomiting in pregnancy; however, the NIH notes the research to date provides little evidence that supplemental B6 reduces cardiovascular or cancer risk, finds insufficient evidence for an effect on cognitive function, and reports that while B6 shows promise for PMS the studies are of poor quality and findings for morning sickness are mixed, so more research is needed before drawing firm conclusions. — per the NIH Office of Dietary Supplements; not medical advice.
The most common vitamin B6 form in supplements is pyridoxine (as pyridoxine hydrochloride [HCl]), though some supplements contain pyridoxal 5'-phosphate (PLP). It is sold in multivitamins, B-complex supplements, and as a stand-alone product, available as oral capsules or tablets (including sublingual and chewable tablets) and liquids. According to the NIH, absorption of vitamin B6 from supplements is similar to that from food sources and does not differ substantially among the various supplement forms.
Vitamin B6 is found in a wide variety of foods, and its richest sources include fish, beef liver and other organ meats, potatoes and other starchy vegetables, and fruit (other than citrus). In the United States, adults obtain most of their dietary vitamin B6 from fortified cereals, beef, poultry, starchy vegetables, and some noncitrus fruits; about 75% of vitamin B6 from a mixed diet is bioavailable — per the NIH Office of Dietary Supplements.
Frank deficiencies are relatively rare in the U.S., but groups most likely to have inadequate vitamin B6 include people with impaired renal function (such as end-stage renal disease or those on dialysis), people with autoimmune disorders like rheumatoid arthritis and malabsorptive conditions (celiac disease, Crohn's disease, ulcerative colitis), and people with alcohol dependence. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function; in infants it can cause irritability, abnormally acute hearing, and convulsive seizures — per the NIH Office of Dietary Supplements.
High intakes of vitamin B6 from food sources have not been reported to cause adverse effects, but chronic intake of 1–6 g of oral pyridoxine per day for 12–40 months can cause severe, progressive sensory neuropathy with ataxia; other effects include painful, disfiguring skin lesions, photosensitivity, and gastrointestinal symptoms such as nausea and heartburn. The Food and Nutrition Board set a Tolerable Upper Intake Level (UL) of 100 mg/day for adults, with lower ULs for children and adolescents — per the NIH Office of Dietary Supplements.
Cost per serving
$0.04
Cheap·−82%Cost per serving
$0.08
Avg·−56%Cost per serving
$0.06
Avg·−73%Cost per serving
$0.04
Cheap·−83%Cost per serving
$0.04
Cheap·−83%Cost per serving
$0.27
Cost per serving
$1.99
Cost per serving
$1.16
Cost per serving
$1.61
Cost per serving
$0.07
Avg·−65%Cost per serving
$0.13
Avg·−37%Cost per serving
$0.05
Cheap·−77%Cost per serving
$0.19
PriceyCost per serving
$0.42
PriceyCost per serving
$0.14
Avg·−33%Cost per serving
$0.41
PriceyCost per serving
$0.15
AvgCost per serving
$0.21
PriceyCost per serving
$0.07
Avg·−68%Cost per serving
$0.17
PriceyCost per serving
$0.07
Avg·−67%Cost per serving
$0.16
AvgCost per serving
$0.13
Avg·−35%Cost per serving
$0.07
Avg·−64%Amazon.com · 🧠 Vitamin B6
CPS
Price
$4.99
Amazon.com · 🧠 Vitamin B6
CPS
Price
$9.99
Amazon.com · 🧠 Vitamin B6
CPS
Price
$6.02
Amazon.com · 🧠 Vitamin B6
CPS
Price
$9.97
Amazon.com · 🧠 Vitamin B6
CPS
Price
$9.56
Amazon.com · 🔶 Copper
CPS
Price
$15.99
Amazon.com · 💪 Protein Powder
CPS
Price
$23.91
Amazon.com · 🧠 SAM-e
CPS
Price
$103.99
Amazon.com · 🧠 SAM-e
CPS
Price
$48.39
HerbsPro · 🧠 Vitamin B6
CPS
Price
$16.95
HerbsPro · 🧠 Vitamin B6
CPS
Price
$15.58
HerbsPro · 🧠 Vitamin B6
CPS
Price
$12.91
HerbsPro · 🧠 Vitamin B6
CPS
Price
$11.55
HerbsPro · 🧠 Vitamin B6
CPS
Price
$12.59
HerbsPro · 🧠 Vitamin B6
CPS
Price
$8.39
HerbsPro · 🧠 Vitamin B6
CPS
Price
$24.33
HerbsPro · 🧠 Vitamin B6
CPS
Price
$4.55
HerbsPro · 🧠 Vitamin B6
CPS
Price
$6.29
HerbsPro · 🧠 Vitamin B6
CPS
Price
$6.67
HerbsPro · 🧠 Vitamin B6
CPS
Price
$9.93
HerbsPro · 🧠 Vitamin B6
CPS
Price
$6.83
HerbsPro · 🧠 Vitamin B6
CPS
Price
$9.49
HerbsPro · 🧠 Vitamin B6
CPS
Price
$13.48
HerbsPro · 🧠 Vitamin B6
CPS
Price
$7.19
Dosage, upper-limit, deficiency and interaction facts are sourced from the NIH Office of Dietary Supplements Vitamin B6 fact sheet. General information, not medical advice.