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vitamin · 68 active deals
Every Vitamin B9 deal here is ranked by cost per dose— what you actually pay per serving, not the sticker price. Forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Right now the best value across our full Vitamin B9 catalog is at $0.01 per serving.
Recommended daily intake
Upper limit applies to synthetic folic acid; expressed as mcg DFE. General FDA/NIH adult guidance — not medical advice.
Folate is a water-soluble B vitamin (sometimes called vitamin B9) that functions as a coenzyme or cosubstrate in single-carbon transfers, where it is required for the synthesis of nucleic acids (DNA and RNA) and the metabolism of amino acids; it is involved in converting homocysteine to methionine and in the methylation of deoxyuridylate to thymidylate, a reaction needed for proper cell division. Researchers have studied folate's possible role in several conditions, including autism spectrum disorder, cancer, cardiovascular disease and stroke, dementia and cognitive function, depression, neural tube defects, and preterm birth and other congenital anomalies, but the evidence is largely mixed, observational, or inconclusive. The available evidence suggests that supplementation appears to reduce the risk of stroke, especially in populations with low folate status, while trials generally have not shown that folic acid supplements reduce other cardiovascular events, overall cancer risk, or cognitive decline, and some studies have raised concerns that high folic acid doses taken after preneoplastic lesions are established could promote cancer development. Adequate maternal folate intake is associated with reduced risk of neural tube defects, though firm causal conclusions for most other outcomes require more research — per the NIH Office of Dietary Supplements; not medical advice.
The fact sheet describes three main forms: naturally occurring food folates (in the tetrahydrofolate, or THF, polyglutamate form), folic acid (the fully oxidized monoglutamate form used in fortified foods and most dietary supplements), and 5-MTHF (also called L-methylfolate or methylfolate), found in some supplements. The sheet states that about 85% of supplemental folic acid is bioavailable when taken with food and nearly 100% when taken without food, whereas only about 50% of folate naturally present in food is bioavailable. It notes that the bioavailability of 5-MTHF in supplements is the same as or greater than that of folic acid, although formal conversion factors for 5-MTHF have not been established.
Folate is naturally present in a wide variety of foods, including vegetables (especially dark green leafy vegetables), fruits and fruit juices, nuts, beans, peas, seafood, eggs, dairy products, meat, poultry, and grains. Spinach, liver, asparagus, and brussels sprouts are among the foods with the highest folate levels. Because cereals and grains are widely consumed in the United States and are fortified with folic acid, they have become important contributors of folic acid to the American diet — per the NIH Office of Dietary Supplements.
Isolated folate deficiency is uncommon and usually coexists with other nutrient deficiencies because of its strong association with poor diet, alcoholism, and malabsorptive disorders; its primary clinical sign is megaloblastic anemia (large, abnormally nucleated erythrocytes), with symptoms such as weakness, fatigue, difficulty concentrating, headache, heart palpitations, and shortness of breath. Groups most likely to be at risk of inadequacy include people with alcohol use disorder, women of childbearing age, pregnant women, people with malabsorptive disorders, and those with an MTHFR polymorphism. Women with insufficient folate intakes are at increased risk of giving birth to infants with neural tube defects — per the NIH Office of Dietary Supplements.
Some population groups are at risk of obtaining excessive folic acid, primarily from dietary supplements; for example, about 5% of men and women age 51–70 and men age 71 and older have folic acid intakes exceeding the UL of 1,000 mcg per day, and many children exceed the lower UL of 300–600 mcg per day. Little is known about the long-term effects of high folic acid doses in children — per the NIH Office of Dietary Supplements.
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$1.16
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$1.61
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$0.03
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$0.03
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$0.03
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$0.10
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$0.05
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$0.03
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$0.03
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$0.04
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$0.02
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$0.08
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$0.18
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$0.11
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$0.13
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$0.16
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$0.21
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$0.15
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$0.23
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$0.05
Avg·−70%Cost per serving
$0.07
Avg·−61%Amazon.com · 🔶 Copper
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HerbsPro · 🌿 Vitamin B9
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$6.29
HerbsPro · 🌿 Vitamin B9
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$6.99
HerbsPro · 🌿 Vitamin B9
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Price
$4.95
HerbsPro · 🌿 Vitamin B9
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$9.69
HerbsPro · 🌿 Vitamin B9
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Price
$8.52
HerbsPro · 🌿 Vitamin B9
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Price
$14.47
HerbsPro · 🌿 Vitamin B9
CPS
Price
$14.53
HerbsPro · 🌿 Vitamin B9
CPS
Price
$6.99
HerbsPro · 🌿 Vitamin B9
CPS
Price
$23.97
HerbsPro · 🌿 Vitamin B9
CPS
Price
$8.84
HerbsPro · 🌿 Vitamin B9
CPS
Price
$5.88
HerbsPro · 🌿 Vitamin B9
CPS
Price
$8.05
HerbsPro · 🌿 Vitamin B9
CPS
Price
$16.29
HerbsPro · 🌿 Vitamin B9
CPS
Price
$11.25
HerbsPro · 🌿 Vitamin B9
CPS
Price
$7.99
HerbsPro · 🌿 Vitamin B9
CPS
Price
$14.21
HerbsPro · 🌿 Vitamin B9
CPS
Price
$24.74
HerbsPro · 🌿 Vitamin B9
CPS
Price
$14.54
HerbsPro · 🌿 Vitamin B9
CPS
Price
$13.94
HerbsPro · 🌿 Vitamin B9
CPS
Price
$11.84
HerbsPro · 🌿 Vitamin B9
CPS
Price
$7.45
Dosage, upper-limit, deficiency and interaction facts are sourced from the NIH Office of Dietary Supplements Vitamin B9 fact sheet. General information, not medical advice.
$0.27
