NEW
🧠 Choline
Cost per serving
$0.11
Avg·−56%
other · 22 active deals
The best-value Choline right now is about $0.03 per dose — across 17 tracked products the median is $0.117/dose, so shopping on cost-per-dose can cut your cost several-fold. Every Choline deal here is ranked by cost per dose— what you actually pay per serving, not the sticker price — because forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Right now the best value across our full Choline catalog is at $0.03 per serving.
Recommended daily intake
An essential nutrient most people under-consume; alpha-GPC and citicoline are concentrated forms. General FDA/NIH adult guidance — not medical advice.
Choline is an essential nutrient that serves as a source of methyl groups for many steps in metabolism; the body needs it to synthesize phosphatidylcholine and sphingomyelin, two phospholipids vital for cell membranes, and to produce acetylcholine, a neurotransmitter important for memory, mood, muscle control, and other brain and nervous system functions, as well as for gene expression, cell-membrane signaling, lipid transport and metabolism, and early brain development. According to the NIH Office of Dietary Supplements, choline has been studied for possible roles in cardiovascular and peripheral artery disease, neurological disorders such as cognitive decline and Alzheimer's disease, and nonalcoholic fatty liver disease (NAFLD). The evidence is limited and inconsistent: several large observational studies found no significant association between choline intake and cardiovascular or peripheral artery disease (one analysis even linked higher intake to increased mortality), reviews including a 2015 systematic review and a 2003 Cochrane review found no clear cognitive benefit from choline or lecithin supplements, and while choline deficiency is associated with fat accumulation in the liver, more research is needed to clarify its role in preventing or treating NAFLD. The NIH notes that additional research is needed to determine the potential risks and benefits of choline supplementation for these conditions — per the NIH Office of Dietary Supplements; not medical advice.
According to the NIH Office of Dietary Supplements, choline is sold as supplements containing choline only, in combination with B-complex vitamins, and in some multivitamin/mineral products, with typical amounts ranging from 10 mg to 250 mg. The forms of choline in dietary supplements include choline bitartrate, phosphatidylcholine, and lecithin. No studies have compared the relative bioavailability of choline from these different forms.
The main dietary sources of choline in the United States are primarily animal-based products that are particularly rich in choline — meat, poultry, fish, dairy products, and eggs — while cruciferous vegetables and certain beans are also rich in choline, and other sources include nuts, seeds, and whole grains. Among the foods listed, beef liver (356 mg per 3 ounces) and eggs (147 mg per large egg) are especially high — per the NIH Office of Dietary Supplements.
Choline deficiency can cause muscle damage, liver damage, and nonalcoholic fatty liver disease (NAFLD), though frank deficiency in healthy men and nonpregnant women is very rare. Groups most likely to have inadequate choline status include pregnant women (about 90%–95% consume less than the Adequate Intake), people with certain genetic alterations (SNPs) that raise their dietary choline needs, and patients on long-term total parenteral nutrition — per the NIH Office of Dietary Supplements.
Every Choline deal above is ranked by real cost per dose with no paid placement — see our and .
1 of 8 tracked Choline brands here are flagged as carrying independent third-party testing — a voluntary check of a product's identity, potency and contaminants by an outside lab. It's a quality signal, not a value or efficacy claim. Confirm any brand's current status on the official registries:
Testing status is self-reported by the brand or drawn from public certification and may change — always verify on the official registry before purchase.
There is no for choline; the Food and Nutrition Board set Adequate Intakes (AIs). Adult AIs are 550 mg/day for men and 425 mg/day for women, 450 mg/day in pregnancy and 550 mg/day during lactation. Children's AIs range from 125 mg/day (birth-6 months) to 375 mg/day (9-13 years). — per the NIH Office of Dietary Supplements; general information, not medical advice.
Yes. The is 1,000 mg for ages 1-8, 2,000 mg for 9-13, 3,000 mg for 14-18, and 3,500 mg for adults 19+. High intakes are associated with a fishy body odor, vomiting, excessive sweating and salivation, hypotension, and liver toxicity. — per the NIH Office of Dietary Supplements; general information, not medical advice.
Choline deficiency can cause muscle damage, liver damage, and nonalcoholic fatty liver disease (NAFLD or hepatosteatosis). However, frank choline deficiency in healthy men and nonpregnant women is very rare, possibly because of choline the body synthesizes endogenously. — per the NIH Office of Dietary Supplements; general information, not medical advice.
Groups most likely to have inadequate choline status include pregnant women (about 90%-95% consume less than the AI), people with certain genetic alterations (SNPs in genes for choline, folate, and methionine metabolism that raise dietary choline demands), and patients requiring long-term total parenteral nutrition. — per the NIH Office of Dietary Supplements; general information, not medical advice.
We link primary sources and paraphrase their findings — never copy their text, tables, or images. Cost-per-dose figures are our own first-party catalog data.
High intakes of choline are associated with a fishy body odor, vomiting, excessive sweating and salivation, hypotension, and liver toxicity. The FNB established Tolerable Upper Intake Levels (ULs) — based on amounts linked to hypotension and fishy body odor — of 1,000 mg/day for ages 1–8, 2,000 mg for ages 9–13, 3,000 mg for ages 14–18, and 3,500 mg/day for adults 19 and older — per the NIH Office of Dietary Supplements.
Cost per serving
$0.11
Avg·−56%Cost per serving
$0.12
Avg·−50%180 servings · ~180-day supply
Cost per serving
$0.08
Cheap·−80%400 servings · ~400-day supply
Cost per serving
$0.09
Cheap·−78%200 servings · ~200-day supply
Cost per serving
$0.09
Cheap·−78%100 servings · ~100-day supply
Cost per serving
$0.10
Cheap·−75%100 servings · ~100-day supply
Cost per serving
$0.27
PriceyCost per serving
$1.08
Pricey60 servings · ~60-day supply
Cost per serving
$1.02
Pricey60 servings · ~60-day supply
Cost per serving
$1.50
30 servings · ~30-day supply
Cost per serving
$0.08
480 servings · ~480-day supply
Cost per serving
$0.15
60 servings · ~60-day supply
Cost per serving
$0.56
60 servings · ~60-day supply
Cost per serving
$0.11
240 servings · ~240-day supply
Cost per serving
$0.10
Avg·−72%Cost per serving
$0.14
Cost per serving
$0.40
60 servings · ~60-day supply
Cost per serving
$0.10
Cheap·−75%100 servings · ~100-day supply
Cost per serving
$0.21
Avg·−30%100 servings · ~100-day supply
Cost per serving
$0.22
Avg120 servings · ~120-day supply
Cost per serving
$0.03
Cheap·−92%Cost per serving
$0.14
Avg·−45%Amazon.com · 🧠 Choline
CPS
Price
$26.99
Amazon.com · 🧠 Choline
CPS
Price
$20.99
Amazon.com · 🧠 Choline
CPS
Price
$31.09
Amazon.com · 🧠 Choline
CPS
Price
$17.12
Amazon.com · 🧠 Choline
CPS
Price
$8.56
Amazon.com · 🧠 Choline
CPS
Price
$9.79
Amazon.com · 🧠 Choline
CPS
Price
$31.95
Amazon.com · 🧠 Choline
CPS
Price
$64.99
SuperSmart USA LLC · SuperSmart · 🧠 Choline
CPS
Price
$61.00
GHOST · Amazon.com · 💪 Beta-Alanine
CPS
Price
$44.99
Micro Ingredients · Amazon.com · 🅱️ B-Complex
CPS
Price
$39.99
Amazon.com · 🅱️ B-Complex
CPS
Price
$8.99
Amazon.com · 🅱️ B-Complex
CPS
Price
$33.79
Micro Ingredients · Amazon.com · 🅱️ B-Complex
CPS
Price
$26.95
Micro Ingredients · Amazon.com · 🧠 Choline
CPS
Price
$23.99
BulkSupplements.com · Amazon.com · 🧠 Alpha-GPC
CPS
Price
$22.97
NOW Foods · Amazon.com · 🧠 Alpha-GPC
CPS
Price
$23.91
NOW Foods · Amazon.com · 🧠 Choline
CPS
Price
$9.79
Pure Encapsulations · Amazon.com · 🧠 Choline
CPS
Price
$20.50
Nutricost · Amazon.com · 🧠 Choline
CPS
Price
$26.95
BulkSupplements.com · Amazon.com · 🧠 Choline
CPS
Price
$25.97
Solgar · Amazon.com · 🧠 Choline
CPS
Price
$13.74
Choline is not known to have any clinically relevant interactions with medications. — per the NIH Office of Dietary Supplements; general information, not medical advice.
BulkSupplements.com Choline Bitartrate Powder - Choline Supplements - Unflavored… at $0.03 per serving — the lowest cost-per-dose choline in our catalog. See the full ranking on the Best Choline page.
We're tracking 22 active Choline deals across Amazon US and partner retailers, ranked by community votes and cost-per-dose — not paid placement.
Across 17 tracked Choline deals the median cost-per-dose is $0.117; the cheapest quartile comes in under $0.098 per serving. Anything below the median is a solid deal for the same molecule.
Deals are submitted by the community and ranked by net votes (hot minus cold) plus cost-per-dose normalised across container sizes. We take no affiliate kickbacks for ordering; sponsored slots, when present, are clearly badged.
High intakes of choline are associated with a fishy body odor, vomiting, excessive sweating and salivation, hypotension, and liver toxicity. The FNB established Tolerable Upper Intake Levels (ULs) — based on amounts linked to hypotension and fishy body odor — of 1,000 mg/day for ages 1–8, 2,000 mg for ages 9–13, 3,000 mg for ages 14–18, and 3,500 mg/day for adults 19 and older — per the NIH Office of Dietary Supplements.
The main dietary sources of choline in the United States are primarily animal-based products that are particularly rich in choline — meat, poultry, fish, dairy products, and eggs — while cruciferous vegetables and certain beans are also rich in choline, and other sources include nuts, seeds, and whole grains. Among the foods listed, beef liver (356 mg per 3 ounces) and eggs (147 mg per large egg) are especially high — per the NIH Office of Dietary Supplements.
Dosage, upper-limit, deficiency, food-source and interaction facts are sourced from the NIH Office of Dietary Supplements Choline fact sheet. General information, not medical advice.
240 servings · ~240-day supply
120 servings · ~120-day supply
240 servings · ~240-day supply
166 servings · ~166-day supply
833 servings · ~833-day supply
100 servings · ~100-day supply
