Healthy Origins Cognizin Citicoline 250 mg, 30 Veggie Caps
Healthy OriginsAmazon.com
$0.47/serving
$13.990°
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Choline
other · 81 active deals
How much does Choline cost?
The best-value Choline right now is about $0.03 per dose — across the 48 we can price per dose the median is $0.270/dose, so shopping on cost-per-dose can cut your cost several-fold. Every Choline deal here is ranked by cost per dose — what you actually pay per serving, not the sticker price — because forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Prices checked · live from the Amazon US catalog.
Right now the best value across our full Choline catalog is at $0.03 per serving.
Median $0.270/servingCheapest quartile under $0.150across 48 tracked Choline deals
Recommended daily intake
Daily Value 550 mgUpper limit 3,500 mg
An essential nutrient most people under-consume; alpha-GPC and citicoline are concentrated forms. General FDA/NIH adult guidance — not medical advice.
What Choline does
Choline is an essential nutrient that serves as a source of methyl groups for many steps in metabolism; the body needs it to synthesize phosphatidylcholine and sphingomyelin, two phospholipids vital for cell membranes, and to produce acetylcholine, a neurotransmitter important for memory, mood, muscle control, and other brain and nervous system functions, as well as for gene expression, cell-membrane signaling, lipid transport and metabolism, and early brain development. According to the NIH Office of Dietary Supplements, choline has been studied for possible roles in cardiovascular and peripheral artery disease, neurological disorders such as cognitive decline and Alzheimer's disease, and nonalcoholic fatty liver disease (NAFLD). The evidence is limited and inconsistent: several large observational studies found no significant association between choline intake and cardiovascular or peripheral artery disease (one analysis even linked higher intake to increased mortality), reviews including a 2015 systematic review and a 2003 Cochrane review found no clear cognitive benefit from choline or lecithin supplements, and while choline deficiency is associated with fat accumulation in the liver, more research is needed to clarify its role in preventing or treating NAFLD. The NIH notes that additional research is needed to determine the potential risks and benefits of choline supplementation for these conditions — per the NIH Office of Dietary Supplements; not medical advice.
Forms & absorption
According to the NIH Office of Dietary Supplements, choline is sold as supplements containing choline only, in combination with B-complex vitamins, and in some multivitamin/mineral products, with typical amounts ranging from 10 mg to 250 mg. The forms of choline in dietary supplements include choline bitartrate, phosphatidylcholine, and lecithin. No studies have compared the relative bioavailability of choline from these different forms.
Food sources of Choline
The main dietary sources of choline in the United States are primarily animal-based products that are particularly rich in choline — meat, poultry, fish, dairy products, and eggs — while cruciferous vegetables and certain beans are also rich in choline, and other sources include nuts, seeds, and whole grains. Among the foods listed, beef liver (356 mg per 3 ounces) and eggs (147 mg per large egg) are especially high — per the NIH Office of Dietary Supplements.
Choline deficiency — who's at risk
Choline deficiency can cause muscle damage, liver damage, and nonalcoholic fatty liver disease (NAFLD), though frank deficiency in healthy men and nonpregnant women is very rare. Groups most likely to have inadequate choline status include pregnant women (about 90%–95% consume less than the Adequate Intake), people with certain genetic alterations (SNPs) that raise their dietary choline needs, and patients on long-term total parenteral nutrition — per the NIH Office of Dietary Supplements.
Alpha GPC Choline Supplement 600mg – 180 Vegetarian Capsules
LongLifeNutriAmazon.com
$0.11/serving
$18.900°
X Gold Health Alpha GPC Choline 600mg Nootropic,120 Veggie…
X Gold HealthAmazon.com
$0.22/serving
$26.980°
2 Bottles Choline Bitartrate 900mg Per Serving 180 Total…
KRK SUPPLEMENTSAmazon.com
$0.15/serving
$26.890°
Nested Naturals Choline Bitartrate 500mg Per Serving - High…
Nested NaturalsAmazon.com
$0.11/serving
$39.950°
Vitamatic Choline Bitartrate 800 mg – 180 Vegetable Capsules…
VitamaticAmazon.com
$0.06/serving
$9.990°
Best Naturals Choline Bitartrate 650 mg (Non-GMO) for Healthy…
Best NaturalsAmazon.com
$0.07/serving
$12.990°
Horbaach Choline Bitartrate Supplement | 1000mg | 250 Capsules
HorbäachAmazon.com
$0.07/serving
$17.990°
Bucked Up Alpha GPC 600mg | L Alpha Glycerylphosphorylcholine…
Bucked UpAmazon.com
$0.44/serving
$21.950°
Healthy Origins Cognizin Citicoline 250 mg, 150 Veggie Caps
Healthy OriginsAmazon.com
$0.33/serving
$49.990°
Piping Rock CDP Choline Citicoline 1000mg | 60 Quick Release…
Piping RockAmazon.com
$0.33/serving
$19.890°
Jarrow Alpha GPC, 300mg Choline Supplements, Brain Health…
Jarrow FormulasAmazon.com
$0.58/serving
$34.940°
BulkSupplements.com Alpha GPC Capsules - Acetylcholine…
BulkSupplements.comAmazon.com
$0.24/serving
$21.960°
Every Choline deal above is ranked by real cost per dose with no paid placement — see our and .
Independent testing
3 of 37 tracked Choline brands here are flagged as carrying independent third-party testing — a voluntary check of a product's identity, potency and contaminants by an outside lab. It's a quality signal, not a value or efficacy claim. Confirm any brand's current status on the official registries:
Testing status is self-reported by the brand or drawn from public certification and may change — always verify on the official registry before purchase.
Choline — dosage, safety & deals FAQ
- How much Choline do you need per day?
There is no for choline; the Food and Nutrition Board set Adequate Intakes (AIs). Adult AIs are 550 mg/day for men and 425 mg/day for women, 450 mg/day in pregnancy and 550 mg/day during lactation. Children's AIs range from 125 mg/day (birth-6 months) to 375 mg/day (9-13 years). — per the NIH Office of Dietary Supplements; general information, not medical advice.
- Can you take too much Choline?
Yes. The is 1,000 mg for ages 1-8, 2,000 mg for 9-13, 3,000 mg for 14-18, and 3,500 mg for adults 19+. High intakes are associated with a fishy body odor, vomiting, excessive sweating and salivation, hypotension, and liver toxicity. — per the NIH Office of Dietary Supplements; general information, not medical advice.
- What are the signs of Choline deficiency?
Choline deficiency can cause muscle damage, liver damage, and nonalcoholic fatty liver disease (NAFLD or hepatosteatosis). However, frank choline deficiency in healthy men and nonpregnant women is very rare, possibly because of choline the body synthesizes endogenously. — per the NIH Office of Dietary Supplements; general information, not medical advice.
- Who is most likely to need more Choline?
Groups most likely to have inadequate choline status include pregnant women (about 90%-95% consume less than the AI), people with certain genetic alterations (SNPs in genes for choline, folate, and methionine metabolism that raise dietary choline demands), and patients requiring long-term total parenteral nutrition. — per the NIH Office of Dietary Supplements; general information, not medical advice.
Related supplements
References & sources
- Choline: Fact Sheet for Health Professionals — NIH Office of Dietary Supplements
- USP Verified product participants — U.S. Pharmacopeia
- NSF certified products — NSF
We link primary sources and paraphrase their findings — never copy their text, tables, or images. Cost-per-dose figures are our own first-party catalog data.