Life Extension Same, S-Adenosyl-Methionine, 400 mg, Mood and Liver…
Our verdict
Life Extension Same, S-Adenosyl-Methionine, 400 mg, Mood and Liver… works out to $0.48 per serving of sam-e, at 400mg per serving in tablet form. That puts it below the median of the 24 sam-e products we can price per dose, where the typical serving costs $0.50, a Value Index of 1.1 where the median product is 1.0. One container lasts 60 days at the label dose of 1 serving a day, about $14.25 a month. We could not verify a third-party certification for Life Extension in a public registry. Worked out from the current retail price as of 2026-11-13; confirm the live price on Amazon.com before buying.
Questions about this product
- How much does one serving of Life Extension Same, S-Adenosyl-Methionine, 400 mg, Mood and Liver… cost?
- $0.48 per serving, which is 400mg of sam-e in tablet form, against a typical $0.50 across the 24 sam-e products we can price per dose, a Value Index of 1.1 where the median product is 1.0. Worked out from the current retail price as of 2026-11-13, not the sticker price.
- How long does one container of Life Extension Same, S-Adenosyl-Methionine, 400 mg, Mood and Liver… last?




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The silence is deafening
Lead with cost-per-dose, not vibes.