NEW
🧂 Sodium Bicarbonate
Cost per serving
$0.02
Cheap·−76%
other · 9 active deals
The best-value Sodium Bicarbonate right now is about $0.01 per dose — across 9 tracked products the median is $0.109/dose, so shopping on cost-per-dose can cut your cost several-fold. Every Sodium Bicarbonate deal here is ranked by cost per dose— what you actually pay per serving, not the sticker price — because forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Right now the best value across our full Sodium Bicarbonate catalog is at $0.01 per serving.
Sodium bicarbonate is a chemical compound made of sodium (Na+) and bicarbonate (HCO3−) that works by buffering excess hydrogen ions to raise pH. In an oral, over-the-counter context, it is approved as an antacid to relieve heartburn, acid indigestion, and upset stomach. It is also used medically (often by IV in clinical settings) for conditions such as metabolic acidosis from severe renal disease, uncontrolled diabetes, and severe lactic acidosis, as well as for certain drug toxicities and urinary alkalinization. — per StatPearls (NCBI Bookshelf); not medical advice.
For oral use it comes as tablets (650 mg) and powder (325 mg), where 1 mEq equals 84 mg; for dyspepsia, adults under 60 may take 650 to 2600 mg orally every 4 hours (max 15.6 g/day) and those 60 and older 650 to 1300 mg every 4 hours (max 7.8 g/day). It is also available in intravenous formulations (7.5% and 8.4%) for clinical use.
Reported adverse effects include metabolic alkalosis, headache, muscle pain, nausea, nervousness, and fluid retention with edema (especially in renal insufficiency); IV use can cause tissue damage/necrosis from extravasation and acute pulmonary edema with rapid administration. Rapid or high-dose administration may cause intracranial hemorrhage, particularly in children younger than 2 years. It is contraindicated in metabolic or respiratory alkalosis and in hypocalcemia, and should be used with caution in heart failure and other sodium-retention conditions. — per StatPearls (NCBI Bookshelf).
Oral sodium bicarbonate can reduce gastrointestinal absorption of fluoroquinolones, tetracyclines, NSAIDs, and extended-release formulations, and can increase serum levels of amphetamines via renal reabsorption; intravenously it is incompatible with norepinephrine and dobutamine. In pregnancy there is a potential fluid-retention risk and comprehensive human data are lacking, and no human data are available for breastfeeding. — per StatPearls (NCBI Bookshelf).
Source: NIH Office of Dietary Supplements — Sodium Bicarbonate fact sheet
Every Sodium Bicarbonate deal above is ranked by real cost per dose with no paid placement — see our and .
According to the page, sodium bicarbonate is used to manage acute or chronic metabolic acidosis (related to causes such as severe renal disease, uncontrolled diabetes, severe lactic acidosis, shock, or severe dehydration), and is also used in cardiac arrest, certain drug toxicities (such as barbiturates and toxic alcohols), urinary alkalinization, and for dyspepsia. Its main therapeutic effect is described as increasing plasma bicarbonate to buffer excess hydrogen ions and raise serum pH. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
Sodium bicarbonate is not an essential nutrient with an , so amounts depend entirely on the medical indication. The page lists examples such as oral antacid dosing of 650 to 2600 mg every 4 hours (maximum 15.6 g/day for adults under 60) and 1625 to 2925 mg/day orally divided for chronic renal failure, while acute indications such as metabolic acidosis use intravenous dosing (e.g., 2 to 5 mEq/kg) given under clinical supervision. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
The page lists possible adverse effects including metabolic alkalosis, headache, muscle pain and twitching, nausea or vomiting, slowed breathing, nervousness or restlessness, unpleasant taste, and increased frequency of urination. It also notes more serious risks such as tissue necrosis from extravasation, acute pulmonary edema from rapid administration, and an acute shift in ionized calcium that can cause tetany; rapid injection in neonates and children younger than 2 may cause hypernatremia and possible intracranial hemorrhage. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
We link primary sources and paraphrase their findings — never copy their text, tables, or images. Cost-per-dose figures are our own first-party catalog data.
Cost per serving
$0.02
Cheap·−76%Cost per serving
$0.01
Cheap·−86%1000 servings · ~1000-day supply
Cost per serving
$0.03
Cheap·−75%1000 servings · ~1000-day supply
Cost per serving
$0.21
PriceyCost per serving
$0.12
Avg·−41%Cost per serving
$1.47
Pricey30 servings · ~30-day supply
Cost per serving
$0.11
Avg·−50%Cost per serving
$0.08
Avg·−58%120 servings · ~120-day supply
Cost per serving
$0.13
AvgAmazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$24.69
Amazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$14.06
Amazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$25.87
Amazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$24.97
Amazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$14.04
Amazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$44.15
Amazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$13.12
Amazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$9.99
Amazon.com · 🧂 Sodium Bicarbonate
CPS
Price
$26.27
Per the page, sodium bicarbonate can affect medications including fluoroquinolones (such as levofloxacin) and tetracyclines (such as doxycycline and minocycline), and can increase serum levels of medications such as dextroamphetamine and methamphetamine by increasing renal reabsorption. It also notes that norepinephrine and dobutamine are incompatible with sodium bicarbonate solution, and that sodium bicarbonate and calcium admixtures may result in precipitation. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
The page states it is contraindicated in people with signs of underlying metabolic or respiratory alkalosis or with hypocalcemia, and notes it can exacerbate hypernatremia. It also advises administering it judiciously in people with congestive heart failure, significant renal disease, or sodium retention, with monitoring of serum electrolytes such as calcium. — per StatPearls (NCBI Bookshelf); general information, not medical advice.
Rising Pharma - Sodium Bicarbonate 650mg - Antacid Used for Acid Indigestion at $0.01 per serving — the lowest cost-per-dose sodium bicarbonate in our catalog. See the full ranking on the Best Sodium Bicarbonate page.
We're tracking 9 active Sodium Bicarbonate deals across Amazon US and partner retailers, ranked by community votes and cost-per-dose — not paid placement.
Across 9 tracked Sodium Bicarbonate deals the median cost-per-dose is $0.109; the cheapest quartile comes in under $0.026 per serving. Anything below the median is a solid deal for the same molecule.
Deals are submitted by the community and ranked by net votes (hot minus cold) plus cost-per-dose normalised across container sizes. We take no affiliate kickbacks for ordering; sponsored slots, when present, are clearly badged.
Reported adverse effects include metabolic alkalosis, headache, muscle pain, nausea, nervousness, and fluid retention with edema (especially in renal insufficiency); IV use can cause tissue damage/necrosis from extravasation and acute pulmonary edema with rapid administration. Rapid or high-dose administration may cause intracranial hemorrhage, particularly in children younger than 2 years. It is contraindicated in metabolic or respiratory alkalosis and in hypocalcemia, and should be used with caution in heart failure and other sodium-retention conditions. — per StatPearls (NCBI Bookshelf).
Dosage, upper-limit, deficiency, food-source and interaction facts are sourced from the NIH Office of Dietary Supplements Sodium Bicarbonate fact sheet. General information, not medical advice.
1000 servings · ~1000-day supply
120 servings · ~120-day supply
120 servings · ~120-day supply
120 servings · ~120-day supply
200 servings · ~200-day supply
