Micro Ingredients Extra Strength* Omega-3 Fish Oil Supplements…
Micro IngredientsAmazon.com
$0.08/serving
$23.990°
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Omega-3 EPA/DHA
omega · 91 active deals
How much does Omega-3 EPA/DHA cost?
The best-value Omega-3 EPA/DHA right now is about $0.06 per dose — across the 59 we can price per dose the median is $0.266/dose, so shopping on cost-per-dose can cut your cost several-fold. Every Omega-3 EPA/DHA deal here is ranked by cost per dose — what you actually pay per serving, not the sticker price — because forms and absorption differ, so the cheapest bottle isn’t always the cheapest dose.
Prices checked · live from the Amazon US catalog.
Right now the best value across our full Omega-3 EPA/DHA catalog is at $0.06 per serving.
Median $0.266/servingCheapest quartile under $0.142across 59 tracked Omega-3 EPA/DHA deals
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What Omega-3 EPA/DHA does
Omega-3 fatty acids are polyunsaturated fatty acids—the most-researched being ALA, EPA, and DHA—that play important roles in the body as components of the phospholipids forming cell membranes, with DHA especially concentrated in the retina, brain, and sperm; they also provide energy and are used to form eicosanoids, signaling molecules with wide-ranging functions in the cardiovascular, pulmonary, immune, and endocrine systems. ALA is an essential fatty acid that must be obtained from the diet, and because the body's conversion of ALA to EPA and DHA is very limited, consuming EPA and DHA directly from foods or supplements is the only practical way to raise their levels. The NIH ODS notes that evidence linking higher long-chain omega-3 levels to a reduced risk of several chronic diseases, including coronary heart disease, suggests many Americans could benefit from slightly higher intakes, while classical essential fatty acid deficiency in healthy U.S. individuals is virtually nonexistent. — per the NIH Office of Dietary Supplements; not medical advice.
Forms & absorption
Long-chain omega-3s are sold in supplement formulations including fish oil, krill oil, cod liver oil, and vegetarian algal oil, and may contain omega-3s in several chemical forms: natural triglycerides, free fatty acids, ethyl esters, re-esterified triglycerides, and phospholipids. According to the NIH ODS, omega-3s as re-esterified triglycerides, natural triglycerides, and free fatty acids have somewhat higher bioavailability than ethyl esters, though consumption of all forms significantly increases plasma EPA and DHA levels. Krill oil provides omega-3s primarily as phospholipids, which some studies suggest have somewhat higher bioavailability than those in fish oil while other studies do not, and the bioavailability of DHA from algal oil was found in a small study to be equivalent to that from cooked salmon.
Food sources of Omega-3 EPA/DHA
Plant oils that contain ALA include flaxseed (linseed), soybean, and canola oils, and chia seeds and walnuts also contain ALA. Cold-water fatty fish, such as salmon, mackerel, tuna, herring, and sardines, contain high amounts of long-chain omega-3s (EPA and DHA), whereas lower-fat fish such as bass, tilapia, and cod, as well as shellfish, contain lower levels — per the NIH Office of Dietary Supplements.
Omega-3 EPA/DHA deficiency — who's at risk
A deficiency of essential fatty acids — either omega-3s or omega-6s — can cause rough, scaly skin and dermatitis, and plasma and tissue concentrations of DHA decrease when an omega-3 deficiency is present. However, classical essential fatty acid deficiency in healthy individuals in the United States is virtually nonexistent; clinical signs are usually only found in patients receiving parenteral nutrition that lacks polyunsaturated fatty acids — per the NIH Office of Dietary Supplements.
When and how to take Omega-3 EPA/DHA
Take omega-3 (fish oil) with a meal that contains fat — this improves absorption and cuts down on fishy burps. Splitting the dose across two meals helps too, and keeping the capsules in the freezer reduces reflux for many people.
Can you take Omega-3 EPA/DHA with other supplements?
At high doses omega-3 has a mild blood-thinning effect, so talk to your clinician if you take an anticoagulant or are due for surgery.
Omega-3 EPA/DHA side effects
Fishy aftertaste, burps, or mild stomach upset are the usual complaints — all reduced by taking it with food.
General guidance on timing and absorption, not medical advice. Check with a clinician about your medications and conditions.
Lutein and Zeaxanthin Supplement - AREDS 2 Plus+ Eye Vitamins
FIDERNICAmazon.com
$0.10/serving
$29.990°
Glucosamine Chondroitin MSM Collagen Joint Supplements…
Clean NutraceuticalsAmazon.com
$0.25/serving
$29.840°
InnovixLabs Triple Strength Omega 3 Fish Oil 900 mg EPA DHA…
InnovixLabsAmazon.com
$0.25/serving
$49.950°
Prenatal Vitamins for Women with Folic Acid + Omega 3 DHA…
Nature's NutritionAmazon.com
$0.15/serving
$17.820°
Lutein and Zeaxanthin Supplement - AREDS 2 Plus+ Eye Vitamins…
FIDERNICAmazon.com
$0.13/serving
$19.990°
Nature Made Mens Multivitamin Gummies with Omega-3, 150 Count
Nature MadeAmazon.com
$0.10/serving
$14.990°
NatureWise Extra-Strength Omega 3 Fish Oil Supplement - 1000mg…
NatureWiseAmazon.com
$0.11/serving
$18.990°
Prenatal Vitamins for Women with Folic Acid + Omega 3 DHA…
Nature's NutritionAmazon.com
$0.10/serving
$24.820°
Prenatal Vitamins for Women with Folic Acid + Omega 3 DHA…
Nature's NutritionAmazon.com
$0.21/serving
$12.720°
Puritan's Pride Triple Strength Omega-3 Fish Oil 1400mg
Puritan's PrideAmazon.com
$0.14/serving
$34.720°
Micro Ingredients L-Tyrosine 500 mg Per Serving with Omega-3…
Micro IngredientsAmazon.com
$0.06/serving
$19.990°
Micro Ingredients Phosphatidylserine 600 mg Per Serving
Micro IngredientsAmazon.com
$0.07/serving
$15.990°
NOW Supplements, Krill Oil 500 mg, Phospholipid-Bound Omega-3…
NOW FoodsAmazon.com
$0.27/serving
$32.860°
Micro Ingredients Antarctic Krill Oil 1,000 mg Per Serving
Micro IngredientsAmazon.com
$0.10/serving
$29.950°
NatureBell CoQ10 300mg - 240 Capsules - High-Potency Support…
NatureBellAmazon.com
$0.09/serving
$22.490°
Super Omega 3 1500mg - SuperSmart | EPA & DHA Fish Oil…
SuperSmart USA LLCSuperSmart
$0.30/serving
$27.000°
Arctic Plankton Oil 1000mg - SuperSmart | Patented…
SuperSmart USA LLCSuperSmart
$0.72/serving
$43.000°
Methylated Vitamin B Complex Gummies: 22-in-1 for Daily Energy…
BSSTABBONAmazon.com
$1.59/serving
$34.990°
Vitamin D3 K2 + Calcium Liquid-filled Gummies for Kids & Teens
LILICAREAmazon.com
$0.44/serving
$26.490°
ORGANICS NATURE Black Seed Oil Capsules 1000mg – 60 Cold…
ORGANICS NATUREAmazon.com
$0.58/serving
$34.990°
ENERGYBITS Organic Spirulina Tablets (1000 Algae Tablets)…
ENERGYBITSAmazon.com
$0.13/serving
$130.000°
SUPREME HERBALS, 100% Raw and Pure Moringa Leaf Powder…
SUPREME HERBALSAmazon.com
$0.25/serving
$29.990°
Nordic Naturals Ultimate Omega + CoQ10, Lemon - 120 Soft Gels…
Nordic NaturalsAmazon.com
$0.52/serving
$62.860°
De3 Occasional Eye Dryness rTG Omega 3 Supplement…
PRN Physician Recommended NutriceuticalsAmazon.com
$0.75/serving
$67.750°
Garden of Life Dr. Formulated Advanced Omega Fish Oil - Lemon
Garden of LifeAmazon.com
$0.35/serving
$20.990°
Omega 3 Fish Oil Supplement - 2000 mg Per Serving Containing…
STAW NutritionAmazon.com
$0.33/serving
$19.990°
Every Omega-3 EPA/DHA deal above is ranked by real cost per dose with no paid placement — see our and .
Independent testing
4 of 40 tracked Omega-3 EPA/DHA brands here are flagged as carrying independent third-party testing — a voluntary check of a product's identity, potency and contaminants by an outside lab. It's a quality signal, not a value or efficacy claim. Confirm any brand's current status on the official registries:
Testing status is self-reported by the brand or drawn from public certification and may change — always verify on the official registry before purchase.
Omega-3 EPA/DHA — dosage, safety & deals FAQ
- How much Omega-3 do you need per day?
There is no ; the IOM set Adequate Intakes (AIs) for ALA based on omega-3 intakes in healthy populations. For adults 19-50, that is 1.6 g/day for men and 1.1 g/day for women. Pregnancy is 1.4 g/day and lactation 1.3 g/day. The IOM did not establish specific intake recommendations for or DHA. — per the NIH Office of Dietary Supplements; general information, not medical advice.
- Can you take too much Omega-3?
The IOM set no (UL). High doses (900 mg/day EPA plus 600 mg/day DHA or more for several weeks) might reduce immune function; 2-15 g/day EPA and/or DHA might increase bleeding time. Both the FDA and EFSA consider up to about 5 g/day safe; in two trials, 4 g/day for several years slightly raised atrial fibrillation risk in people with or at high risk of CVD. Mild side effects include bad breath, heartburn, nausea, and diarrhea. — per the NIH Office of Dietary Supplements; general information, not medical advice.
- What are the signs of Omega-3 deficiency?
A deficiency of essential fatty acids, either omega-3s or omega-6s, can cause rough, scaly skin and dermatitis. Plasma and tissue concentrations of DHA decrease when an omega-3 deficiency is present, but there are no known cut-off concentrations of DHA or below which functional endpoints are impaired. — per the NIH Office of Dietary Supplements; general information, not medical advice.
- Who is most likely to need more Omega-3?
Classical essential fatty acid deficiency in healthy individuals in the United States is virtually nonexistent. Clinical signs of deficiency are usually found only in patients receiving parenteral nutrition that lacks PUFAs, though all current enteral and parenteral feeding solutions contain adequate PUFAs. Evidence suggests many Americans could benefit from slightly higher intakes. — per the NIH Office of Dietary Supplements; general information, not medical advice.
Omega-3 EPA/DHA guides
Related omega fatty acids
References & sources
- Omega-3 Fatty Acids: Fact Sheet for Health Professionals — NIH Office of Dietary Supplements
- USP Verified product participants — U.S. Pharmacopeia
- NSF certified products — NSF
We link primary sources and paraphrase their findings — never copy their text, tables, or images. Cost-per-dose figures are our own first-party catalog data.