Vitamin B12 (Cobalamin)

Yes. Gastric acid inhibitors (proton pump inhibitors like omeprazole and lansoprazole, and H2 antagonists like cimetidine and ranitidine) can interfere with vitamin B12 absorption from food and lead to deficiency. Metformin might reduce vitamin B12 absorption and significantly lower serum concentrations. — per the NIH Office of Dietary Supplements; general information, not medical advice.

The cheapest vitamin b12 (cobalamin) we track works out to $0.02 , against a typical $0.14 across the 141 we can price per dose — about $0.74 a month at the cheapest. That is real from live Amazon US prices, not the sticker price. The full ranking is on the Best Vitamin B12 (Cobalamin) page.

VITBOOST Vitamin B12 1000 mcg Chewable - 365 Count Natural Berry Flavor… at $0.02 — the lowest cost-per-dose vitamin b12 (cobalamin) in our catalog. See the full ranking on the Best Vitamin B12 (Cobalamin) page.

We're tracking 197 active Vitamin B12 (Cobalamin) deals across Amazon US and partner retailers, ranked by community votes and cost-per-dose — not paid placement.

Across the 141 Vitamin B12 (Cobalamin) deals we can price per dose (combination products are left out — their single label dose belongs to whichever ingredient the product is built around) the median cost-per-dose is $0.141; the cheapest quartile comes in under $0.069 . Anything below the median is a solid deal for the same molecule.

Deals are submitted by the community and ranked by net votes (hot minus cold) plus cost-per-dose normalised across container sizes. We take no affiliate kickbacks for ordering; sponsored slots, when present, are clearly badged.

There is no for B12, so dosing aims to correct a shortfall — 500–1,000 mcg/day orally is common, with higher or sublingual doses when absorption is impaired (older adults, metformin, plant-based diets). If your level is normal, extra B12 will not boost energy. General reference, not medical advice.

Groups most likely to be deficient include older adults (especially those with atrophic gastritis), people with pernicious anemia, people with gastrointestinal disorders such as celiac or Crohn's disease, those who have had gastrointestinal surgery, people who follow vegetarian or vegan diets, and the breastfed infants of women who follow vegan diets. Effects can include megaloblastic anemia, fatigue, glossitis of the tongue, palpitations, low blood cell counts, and neurological changes such as numbness and tingling in the hands and feet, with early intervention important to avoid irreversible damage. Because the body stores about 1 to 5 mg of vitamin B12, symptoms can take several years to appear — per the NIH Office of Dietary Supplements.

Vitamin B12 is present naturally in foods of animal origin, including fish, meat, poultry, eggs, and dairy products. The richest sources listed are beef liver and clams; oysters and fortified nutritional yeasts are also very high. Plant foods do not naturally contain vitamin B12, but fortified breakfast cereals and fortified nutritional yeasts are readily available sources with high — per the NIH Office of Dietary Supplements.